Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis

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#cimicifuga #female #hot-flashes #humans #menopause

Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis

Shams et al., 2010 | Altern Ther Health Med | Meta Analysis

Citation

Shams Taghreed, Setia Maninder Singh, ... Ciampi Antonio. Efficacy of black cohosh-containing preparations on menopausal symptoms: a meta-analysis. Altern Ther Health Med. 2010;16(1):36-44

Abstract

This study aimed to review the evidence on the efficacy of herbal preparations containing black cohosh for the treatment of menopausal symptoms. A systematic search of three databases (PubMed, Embase, and Cochrane library) was conducted to identify relevant literature. Two reviewers independently abstracted the data from the eligible studies. Of the 288 English language citations screened, nine randomized placebo-controlled trials were included. Among these trials, six demonstrated a significant improvement in the black cohosh group compared with the placebo group. Using data from seven trials, we calculated a combined estimate for the change in menopausal vasomotor symptoms. Preparations containing black cohosh improved these symptoms overall by 26% (95% confidence interval 11%-40%); there was, however, significant heterogeneity between these trials. Given that black cohosh is one of the most frequently used herbal medications for menopausal vasomotor symptoms in North America, more data are warranted on its effectiveness and safety.

Key Findings

Given that black cohosh is one of the most frequently used herbal medications for menopausal vasomotor symptoms in North America, more data are warranted on its effectiveness and safety.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Cimicifuga
  • Female
  • Hot Flashes
  • Humans
  • Menopause
  • Middle Aged
  • Nonprescription Drugs
  • Phytotherapy
  • Plant Preparations
  • Randomized Controlled Trials as Topic
  • Treatment Outcome
  • Women's Health

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't, Review
  • Vertical: black-cohosh

Provenance

  • PMID: 20085176
  • DOI: (not available)
  • PMCID: Not in PMC
  • Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09