Green tea consumption and breast cancer risk or recurrence: a meta-analysis
Green tea consumption and breast cancer risk or recurrence: a meta-analysis
Ogunleye et al., 2010 | Breast Cancer Res Treat | Meta Analysis
Citation
Ogunleye Adeyemi A, Xue Fei, Michels Karin B. Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat. 2010-Jan;119(2):477-84. doi:10.1007/s10549-009-0415-0
Abstract
Green tea is a commonly consumed beverage in Asia and has been suggested to have anti-inflammatory and possible anti-carcinogenic properties in laboratory studies. We sought to examine the association between green tea consumption and risk of breast cancer incidence or recurrence, using all available epidemiologic evidence to date. We conducted a systematic search of five databases and performed a meta-analysis of studies of breast cancer risk and recurrence published between 1998 and 2009, encompassing 5,617 cases of breast cancer. Summary relative risks (RR) were calculated using a fixed effects model, and tests of heterogeneity across combined studies were conducted. We identified two studies of breast cancer recurrence and seven studies of breast cancer incidence. Increased green tea consumption (more than three cups a day) was inversely associated with breast cancer recurrence (Pooled RR = 0.73, 95% CI: 0.56-0.96). An analysis of case-control studies of breast cancer incidence suggested an inverse association with a pooled RR of 0.81 (95% CI: 0.75, 0.88) while no association was found among cohort studies of breast cancer incidence. Combining all studies of breast cancer incidence resulted in significant heterogeneity. Available epidemiologic evidence supports the hypothesis that increased green tea consumption may be inversely associated with risk of breast cancer recurrence. The association between green tea consumption and breast cancer incidence remains unclear based on the current evidence.
Key Findings
The association between green tea consumption and breast cancer incidence remains unclear based on the current evidence.
Outcomes Measured
- inflammatory markers
Population
| Field | Value |
|---|---|
| Population | See abstract |
| Sample Size | See abstract |
| Age Range | See abstract |
| Condition | See abstract |
MeSH Terms
- Anticarcinogenic Agents
- Breast Neoplasms
- Camellia sinensis
- Dose-Response Relationship, Drug
- Evidence-Based Medicine
- Female
- Humans
- Incidence
- Neoplasm Recurrence, Local
- Risk Assessment
- Risk Factors
- Tea
Evidence Classification
- Level: Meta Analysis
- Publication Types: Journal Article, Meta-Analysis, Review
- Vertical: green-tea
Provenance
- PMID: 19437116
- DOI: 10.1007/s10549-009-0415-0
- PMCID: Not in PMC
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09