Glucosamine and chondroitin for osteoarthritis?

McAlindon et al., 2001 | Bull Rheum Dis | Meta Analysis

Citation

McAlindon T. Glucosamine and chondroitin for osteoarthritis?. Bull Rheum Dis. 2001-Jul;50(7):1-4

Abstract

The current body of evidence currently supports modest efficacy for glucosamine and chondroitin in the treatment of OA symptoms. The products are safe and could play a valuable role in the management of this disorder. Nevertheless, further independent studies are needed to confirm these findings and to determine the clinical applicability of these compounds. Physicians need to become involved in these treatment decisions but are confused by wide variability in the formulation and purity of the numerous preparations available to consumers. The notion that glucosamine and chondroitin might have disease-modifying effects in OA is highly appealing and supported by preliminary data. Research is needed to confirm these findings and to evaluate the impact of glucosamine and chondroitin on all aspects of OA progression.

Key Findings

Research is needed to confirm these findings and to evaluate the impact of glucosamine and chondroitin on all aspects of OA progression.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Chondroitin
  • Dietary Supplements
  • Glucosamine
  • Humans
  • Osteoarthritis
  • Safety

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't
  • Vertical: glucosamine

Provenance

  • PMID: 11530541
  • DOI: (not available)
  • PMCID: Not in PMC
  • Verified: 2026-04-10 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-10