Tranexamic Acid for The Management of Bleeding Gastrointestinal Angioectasias
Tranexamic Acid for The Management of Bleeding Gastrointestinal Angioectasias
NCT ID: NCT07125508 Phase: PHASE2 Status: COMPLETED Enrollment: 40 Completion: 2024-12-15
Conditions
Anemia, Small Bowel Bleeding, Angioectasias
Interventions
Tranexamic Acid (TXA) treatment, Placebo
Summary
The goal of this clinical trial is to learn if oral tranexamic acid works to treat gastrointestinal angioectasias. It will also learn about the safety of tranexamic acid. The main questions it aims to answer are:
Does tranexamic improve hemoglobin concentration and/or requirement for blood transfusions
What medical problems do participants have when taking tranexamic acid?
Researchers will compare tranexamic acid to a placebo (a look-alike substance that contains no drug) to see if it works to treat angioectasias.
Participants will:
Take tranexamic acid or a placebo three times per day, every day for 3 months Visit the clinic once per month for checkups and tests
Primary Outcome
Number of participants with improved hemoglobin concentrations and/or blood transfusions requirement