Efficacy of Triticum Aestivum Over Vascular Function in Mexican Obese Patients
Efficacy of Triticum Aestivum Over Vascular Function in Mexican Obese Patients
NCT ID: NCT06950138 Phase: PHASE3 Status: COMPLETED Enrollment: 20 Completion: 2025-02-05
Conditions
Obesity, Vascular Risk
Interventions
Triticum aestivum, calcined magnesia
Summary
This study aims to evaluate the efficacy of Triticum aestivum as a treatment for improving the vascular function in Mexican obese patients. We conducted a triple-blind, randomized, placebo controlled clinical trial, involving obese individuals from the metropolitan area of Guadalajara. The participants were randomly assigned to either Triticum aestivum (intervention group) or placebo supplementation (control). The primary outcome measures were those related with the vascular function using non-invasive methods such as flow-mediated dilation and wave pulse velocity measurements. Secondary outcomes included changes in anthropometric or clinical measures, laboratory results and molecular markers (endothelin-1 and nitric oxide). Data were collected at baseline and after the intervention period. Statistical analyses were performed to determine the significance of the observed changes.
Primary Outcome
Wave Pulse Velocity