Impact of Collagen Supplements on Dermal Collagen in Plastic and Bariatric Surgery Patients
Impact of Collagen Supplements on Dermal Collagen in Plastic and Bariatric Surgery Patients
NCT ID: NCT06787924 Phase: NA Status: COMPLETED Enrollment: 102 Completion: 2025-12-15
Conditions
Bariatric Surgery, Abdominoplasty, Collagen Synthesis, Skin Physiology, Randomized Controlled Trial, Tissue Remodeling
Interventions
Collagen hydrolyzed peptides, Starch
Summary
This study aims to evaluate the effects of oral collagen supplementation on dermal collagen content in skin biopsies of patients undergoing abdominoplasty. Using a randomized controlled trial (RCT) design, participants from metabolic bariatric surgery (MBS) and plastic surgery groups will receive either collagen supplements or a placebo for several weeks. Biopsies will be collected pre-intervention and during surgery to compare collagen levels between groups and to baseline. The primary objective is to determine if collagen supplementation significantly enhances dermal collagen deposition compared to placebo and initial levels.
Primary Outcome
Assessment of Wound Healing Parameters vascularity