Effects of Astaxanthin Supplementation
Effects of Astaxanthin Supplementation
NCT ID: NCT06511960 Phase: NA Status: COMPLETED Enrollment: 24 Completion: 2024-04-15
Conditions
Dietary Supplements
Interventions
Astaxanthin (12 mg/day) intervention, 36 mg/day astaxanthin intervention, Placebo
Summary
Astaxanthin is a potent antioxidant and anti-inflammatory carotenoid. Research examining whether astaxanthin (AX) could counteract exercise-induced muscle damage and improve exercise capacity reported inconsistent results.Therefore, the aim of this study was to explore the impact of 4 weeks supplementation with AX on muscle damage markers, total antioxidant status, and subjective marker of muscle pain. Twenty-four males were randomly assigned to the AX12 group (12 mg/day; n=8), AX36 group (36 mg/day; n=9), or placebo group (PLC; n=7). After 4 weeks of supplementation, blood samples were collected at rest, immediately after, and at 2, 24, 48, and 72 hours following eccentric arm exercise at 85% of predetermined one repetition maximum to assess muscle damage markers (creatine kinase and lactate dehydrogenase), total antioxidant status (malondialdehyde and uric acid), and muscle pain levels were evaluated using the Numerical Visual Pain Scale0-10.
Primary Outcome
Assessment of Muscle Pain