Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation.
Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation.
NCT ID: NCT06439875 Phase: NA Status: COMPLETED Enrollment: 101 Completion: 2026-03-09
Conditions
Chronic Obstructive Pulmonary Disease, Respiratory Failure
Interventions
effect of L-arginine and liposomial vitamin C on pulmonary rehabilitation, placebo
Summary
The hypothesis that is being tested is that the supplementation of L-arginine plus Vitamin C to multidisciplinary pulmonary rehabilitation (PR) in patients with a previous diagnosis of chronic obstructive pulmonary disease (COPD) and chronic respiratory failure can have a favorable influence on fatigue and on clinical indicators related to endothelial function, potentially mitigating the cardiovascular (CV) disease burden in this clinical context.
Primary Outcome
Fatigue Severity Scale