Urolithin A Supplementation in Middle-aged Adults With Obesity
Urolithin A Supplementation in Middle-aged Adults With Obesity
NCT ID: NCT05921266 Phase: NA Status: COMPLETED Enrollment: 50 Completion: 2025-05-14
Conditions
Obesity, Vascular Dementia, Cognitive Impairment
Interventions
Urolithin A, Placebo
Summary
The goal of this clinical trial is to learn about the effect of urolithin A, a dietary supplement, on blood flow in middle-aged adults with obesity. The main question it aims to answer is:
- Does urolithin A supplementation improve blood flow in large and small blood vessels in middle-aged adults with obesity?
Participants will be asked to:
- Take the dietary supplement daily for 4 weeks
- Attend two study visits to have their blood vessels checked, answer questionnaires, and give a sample of blood
Researchers will compare people who took the dietary supplement with others who took a placebo to see if the blood flow in the blood vessels improved.
Primary Outcome
Change in arterial function and local stiffness