Metabolic Changes Induced by NMN in Healthy Subjects With Acute Binge Drink

NCT ID: NCT05882214 Phase: PHASE1 Status: COMPLETED Enrollment: 22 Completion: 2025-04-06

Conditions

Binge Drinking, Liver Injury, Nutritional Supplementation, Hepatic Steatosis

Interventions

β-nicotinamide Mononucleotide, Maltodextrin

Summary

The goal of this double-blinded, randomized, crossover trial is to investigate the effects of NMN supplementation on liver function, liver fat content and lipid metabolism in healthy young subjects with acute binge drink. The main questions it aims to answer are:

  1. if NMN administration could accelerate alcohol metabolism and alleviate hangover symptom;
  2. if NMN administration could alleviate alcohol-induced liver injury and hepatic steatosis.

Primary Outcome

Ethanol concentration

Source

ClinicalTrials.gov