Can Biotin Supplementation be Used to Mask hCG Abuse?

Can Biotin Supplementation be Used to Mask hCG Abuse?

NCT ID: NCT05450900 Phase: EARLY_PHASE1 Status: COMPLETED Enrollment: 10 Completion: 2023-02-02

Conditions

Healthy

Interventions

Choriogonadotropin Alpha, biotin, Microcellulose filler

Summary

This sponsor is an anti-doping laboratory tasked with testing athlete samples for prohibited substances by the World Anti-Doping Agency and other agencies.

This study is intended to measure:

  1. Urinary/serum hCG (human chorionic gonadotropin) and urinary biotin concentrations in both treatment groups before, during, and after hCG intervention using standard immunoassay methods
  2. To monitor hCG in both treatment groups before and after diafiltration of urine samples prior to analysis
  3. To compare urinary and serum detectability (detection window, sensitivity) of hCG abuse in the hCG-only group compared to the hCG + biotin group

Primary Outcome

  1. Urinary hCG and biotin concentrations

Source

ClinicalTrials.gov