Nutrition, Immunity, and Covid-19 in Obese People
Nutrition, Immunity, and Covid-19 in Obese People
NCT ID: NCT04979065 Phase: PHASE2 Status: COMPLETED Enrollment: 93 Completion: 2022-12-30
Conditions
Vitamin D Deficiency, Covid19, Overweight and Obesity, Immune Deficiency
Interventions
Probiotics, Vitamin D, Placebo
Summary
The increased risk of transmission of COVID-19 infection causes the incidence of death in health workers to escalate. It requires further research on risk factors and intervention in health worker professionals, especially on immunity factors and nutritional status. Quality of diet and nutrition is very important to support the immune system when infected. Several probiotic strains have been shown to decrease the duration and incidence of diarrhea and respiratory infections, suggesting the Gut-Lung Axis pathway. Some probiotics also improve the balance of diversity in the composition of the gut microbiota and affect body weight in obese people. Probiotics have also been shown to improve vitamin D absorption. A combination of vitamin D and probiotics may be an alternative to reduce gut dysbiosis that will directly or indirectly reduce the risk and severity of viral infections including SARS-CoV-2.
Primary Outcome
Zonulin level