Effect of 60-days Saccharomyces Boulardii and Superoxide Dismutase Supplementation in Obese Adults
Effect of 60-days Saccharomyces Boulardii and Superoxide Dismutase Supplementation in Obese Adults
NCT ID: NCT04919850 Phase: NA Status: COMPLETED Enrollment: 25 Completion: 2020-06-20
Conditions
Obesity, Superoxide Dismutase
Interventions
Saccharomyces boulardii and SOD, Placebo
Summary
In animals it has been demonstrated that Saccharomyces boulardii decrease low-grade inflammation and fat mass; also Superoxide Dismutase (SOD) decrease low-grade inflammation. Therefore, the aim of this double-blind, placebo-controlled clinical trial was to assess the effect of a 60-days S. boulardii and SOD supplementation on circulating markers of inflammation, body composition, hunger sensation, pro/antioxidant ratio, hormonal, lipid profile, glucose, insulin and HOMA-IR, in obese adults (BMI 30-35 kg/m2).
Primary Outcome
Change on concentration of biochemical parameters for hunger sensation and hormonal status