Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
NCT ID: NCT04633551 Phase: NA Status: COMPLETED Enrollment: 9 Completion: 2022-05-30
Conditions
Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
Interventions
Anti-inflammatory supplement
Summary
Women who had an adverse pregnancy outcome (APO), such as preeclampsia, preterm birth, or gestational diabetes, have a higher risk for heart disease. Some of the extra risk for heart disease after APOs is thought to be caused by inflammation. Investigators will randomize women who had an APO in the past 3 years to receive an anti-inflammatory supplement or serve as a time control. Investigators will compare blood pressure, arterial stiffness, blood vessel reactivity, and blood markers of inflammation between women who did and did not receive the supplement. Investigators will determine women's attitudes about taking a dietary supplement and measure whether the participants who receive the supplement take all or most of the doses.
Primary Outcome
Blood Pressure (mmHg)