Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD
Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD
NCT ID: NCT04482465 Phase: NA Status: COMPLETED Enrollment: 50 Completion: 2017-10-05
Conditions
Age-related Macular Degeneration, Vitamin D Deficiency
Interventions
blood sample
Summary
Objectives: The investigators conducted a prospective study in Belgium with the objective to determine the proportion of subjects identified at moderate-to-high risk for AMD, based on the STARS® questionnaire, in need of nutritional supplementation by assessing their vitamin D, zinc oxide and fatty acid profile status.
Methods: This multicentre epidemiological intervention pilot study involved 50 Belgian subjects with no AMD or early AMD, aged over 55, at moderate-to-high risk for AMD based on a simplified AMD risk assessment scale (STARS®) score ≥ 10, not taking vitamin D or trace nutrient containing supplements. Outcome data was collected during a one-time subject interview comprising of clinical eye examinations (typically visual acuity), the STARS® questionnaire, visual acuity assessment, an OCT scan on the macula, and fundus photography. Blood samples were collected from the patients and serum analysis was performed to determine the levels of omega-6 to omega-3 ratio, EPA and DHA, zinc and cupric oxide, and vitamin D, recognised as key nutrients involved in AMD pathophysiology.
Primary Outcome
concentration of vitamin D