Effects of Enzymatic Digestion and Probiotic on Oleuropein Bioavailability

NCT ID: NCT04328571 Phase: NA Status: COMPLETED Enrollment: 104 Completion: 2021-09-15

Conditions

Healthy Subjects

Interventions

OLE enzymatically treated, OLE + probiotic, OLE

Summary

This is a 3-arms randomized-controlled, parallel group, single center, double-blind study investigating the bioavailability of olive oil extract (OLE) in two different OLE formulations (enzymatically treated and co-administered with a probiotic) compared to original OLE formulation in healthy adult subjects.

Primary Outcome

AUC0-24h of individual blood oleuropein metabolites during PK2 period

Source

ClinicalTrials.gov