The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling
The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling
NCT ID: NCT03986307 Phase: NA Status: COMPLETED Enrollment: 23 Completion: 2019-05-25
Conditions
Aging
Interventions
Omega-3 polyunsaturated fatty acid supplementation, Resistance exercise, Placebo - appearance-matched oil supplementation
Summary
Elderly are supplemented with either Omega-3 (3 x 1.1g per day) or placebo (corn oil) during 14 weeks. The last 12 weeks, supplementation is combined with resistance exercise training (3x per week) focusing on upper leg strength. In the present project, the investigators study whether differences in muscle strength and/or muscle mass between conditions can be explained by omega-3-induced effects on systemic or muscle inflammatory signaling, or differences in muscle molecular signaling.
Primary Outcome
Isometric muscle strength