Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes
Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes
NCT ID: NCT03893864 Phase: PHASE1 Status: COMPLETED Enrollment: 22 Completion: 2019-02-28
Conditions
Coenzyme Q10, Oxidative Stress, Aging
Interventions
Administration of a product with Fitosomed Ubiquinone, Coenzyme Q10 level in muscle biopsies, Coenzyme Q10 level in plasma, blood cells, urine cells, Total antioxidant capacity after strenous exercise
Summary
It is proposed to establish a group of subjects composed of 10 healthy individuals of> 50 years and \<65, physically active, without metabolic or inflammatory pathology. All of them will undergo a health examination and the physical condition and the absence of contraindication of the sports practice will be characterized through a monitored effort test. Each subject will take a capsule of coenzyme Q10® INDENA for 30 days. The dose to be administered is 100 mg/d of CoQ10 a with food (noon). The state of physical condition and the biochemical and biological variables that reflect oxidative stress and mitochondrial functioning before and after the intervention will be measured.
Primary Outcome
Change in the concentration of CoQ10 on different tissues after supplementation for a month