Periodized Rehabilitation and Beta-alanine Supplementation in Multiple Sclerosis
Periodized Rehabilitation and Beta-alanine Supplementation in Multiple Sclerosis
NCT ID: NCT03803800 Phase: NA Status: COMPLETED Enrollment: 31 Completion: 2019-12-09
Conditions
Multiple Sclerosis
Interventions
Classic, progressive endurance training, Periodized exercise training, beta-alanine
Summary
Exercise therapy and increased physical activity in persons with Multiple Sclerosis (MS) improves mobility, muscular strength, physical fitness and fatigue without increasing relapse rate. As such, physical activity and more particular exercise therapy have become an important part of MS rehabilitation. Despite the fact that the positive effects of exercise therapy in MS are obvious only 43 percent of the MS community reports to participate in an exercise program4. Therefore, new exercise therapy approaches that further optimize rehabilitation, improve exercise adherence and promote participation in physical exercise in MS are interesting to explore. Therefore, the randomized controlled trial investigates two types of exercise interventions (classic progressive vs periodized) with or without the addition of ergogenic supplements (beta-alanine vs placebo).
Primary Outcome
Exercise capacity