Grape Pomace Polyphenols and Cardiometabolic Risk
Grape Pomace Polyphenols and Cardiometabolic Risk
NCT ID: NCT03076463 Phase: NA Status: COMPLETED Enrollment: 49 Completion: 2017-12-20
Conditions
Subjects at Cardiometabolic Risk
Interventions
GRAPOM
Summary
The aim of this is study is to evaluate the long-term effects of grape polyphenols in the modulation of markers of metabolic syndrome. Most of the previous works about polyphenols have only considered a fraction of polyphenols, i.e., extractable polyphenols. As a consequence, an important amount of dietary polyphenols, the so-called non-extractable polyphenols are ignored. In contrast, the effect of both extractable and non-extractable polyphenols will be considered in this study. Also, studies on the long-term effect of grape polyphenol on markers of metabolic syndrome have been mostly conducted in animals, so clinical trials on this topic are needed.
Primary Outcome
Fasting insulin