Effects of Vitamin D3 Supplementation on Cognitive Function in Community Dwelling Older Adults
Effects of Vitamin D3 Supplementation on Cognitive Function in Community Dwelling Older Adults
NCT ID: NCT02804841 Phase: NA Status: COMPLETED Enrollment: 60 Completion: 2016-11
Conditions
Healthy
Interventions
Cholecalciferol -Vitamin D3, Placebo -gel capsule containing no vitamin D.
Summary
Ireland is predicted to have the highest older adult population growth of any European Union country. A substantial economic and social challenge of this projected growth is the increased incidence of cognitive impairment and the likelihood of progression to dementia. Dementia's, such as Alzheimer's disease, typically have a long prodromal stage with brain changes identifiable from the earliest stages of neuropathology, providing an opportunity for intervention. Switching to a strategy of earlier identification and prevention would significantly reduce prevalence and the associated cost.
The purpose of this pilot study is to evaluate the use of vitamin D supplements in community dwelling older adults as a lifestyle approach that may support cognitive and physical functioning. The research will incorporate several stages including an initial in-depth screening process, a novel and sensitive cognitive battery, 6 month double blind placebo controlled intervention of vitamin D3 (cholecalciferol) and a concluding participant feedback interview.
These results will be used to assess the feasibility of recruiting and assessing community dwelling older adults for extensive nutrition related cognitive studies.
Primary Outcome
Global Cognitive Function