Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes
Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes
NCT ID: NCT02786823 Phase: PHASE2 Status: COMPLETED Enrollment: 80 Completion: 2017-09-15
Conditions
Diabetes Mellitus, Type 2
Interventions
Folic acid, Vitamin B12, Oral hypoglycemic agents [Metformin +/- Sulfonylurea]
Summary
This study aims to evaluate the effect of Folic acid and Vitamin B12 supplementation on Biochemical parameters in subjects with type-2 Diabetes. 80 selected subjects will be divided into 4 groups of 20 each.
- Group A: to receive Folic acid 5 mg once daily for 8 weeks along with standard oral anti-diabetic drugs;
- Group B: to receive Vitamin B12 500 mcg once daily for 8 weeks along with standard oral anti-diabetic drugs;
- Group C: to receive both Folic acid 5 mg once daily and Vitamin B12 500 mcg once daily for 8 weeks along with standard oral anti-diabetic drugs;
- Group D: to receive no additional intervention apart from standard oral anti-diabetic drugs.
The biochemical parameters will be evaluated before and after the intervention.
Primary Outcome
HbA1c