Nutritional Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Muscle Atrophy
Nutritional Rehabilitation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Muscle Atrophy
NCT ID: NCT01344135 Phase: NA Status: COMPLETED Enrollment: 81 Completion: 2015-06
Conditions
Pulmonary Disease, Chronic Obstructive, Muscular Atrophy
Interventions
Dietary supplementation, Placebo supplement, Nutritional counselling, Feedback on physical activity level
Summary
To study in clinically stable Chronic Obstructive Pulmonary Disease (COPD) patients with muscle atrophy:
- The short-term effects of 4 months exercise training including nutritional supplementation versus exercise training alone on physical functioning (skeletal muscle strength and exercise capacity) and body composition.
- The long-term effects of 4 months of exercise training and nutritional supplementation followed by 8 months of nutritional counseling (with supplementation on advice) and feedback on physical activity level versus 4 months of exercise training and 8 months with feedback on physical activity level alone on physical functioning, body composition and cardiometabolic risk profile;
- The cost-effectiveness of exercise rehabilitation and nutritional intervention versus exercise rehabilitation alone.
Primary Outcome
Skeletal muscle strength