Investigating the Acute Effects of Flavonoids in Blueberries on Cognitive Function.

NCT ID: NCT01289860 Phase: NA Status: COMPLETED Enrollment: 47 Completion: 2013-01

Conditions

Healthy Adults.

Interventions

Flavonoids, Control

Summary

This study was a controlled, cross-over, acute flavonoid intervention trial with younger and older adults. Subjects consumed a blueberry beverage during one visit and a control beverage on another. Cognitive function pre drink was assessed, blood and urine samples were taken as well as blood pressure and a measure of vascular reactivity. These outcome measures were taken at 2 and 5 hours post drink.

It was predicted that the flavonoids in the blueberry drink would lead to improved performance on the cognitive tests and vascular reactivity measure compared to following the control drink. It was thought this could be due to increased vaso-dilation and improving blood flow to the brain which was investigated in an extension to the project where a sample of individuals underwent brain imaging in an MRI scanner pre and post a blueberry and a control drink.

Primary Outcome

Cognitive function

Source

ClinicalTrials.gov