Effect of Vitamin D Replacement on Insulin Sensitivity
Effect of Vitamin D Replacement on Insulin Sensitivity
NCT ID: NCT01268111 Phase: PHASE1 Status: COMPLETED Enrollment: 12 Completion: 2012-03
Conditions
Insulin Sensitivity
Interventions
Ergocalciferols, Placebo
Summary
Healthy subjects with low Vitamin D levels will be randomly assigned to either Vitamin D replacement or placebo for a period of 8 weeks. Insulin sensitivity will be measured before and after the intervention, and the changes will be compared between the two groups. This will help us understand if Vitamin D replacement improves insulin sensitivity. Serum Retinol Binding Protein 4 levels will also be measured to see if changes in insulin sensitivity are mediated by RBP4.
Primary Outcome
M Value (Insulin Stimulated Glucose Uptake)