Kava × Ssri

Severity: MODERATE Evidence: possible

Mechanism

Kava may have weak MAO-inhibiting properties; combined with SSRIs may increase serotonin levels.

Effect

Possible serotonin syndrome

Management

Avoid combination. Use caution with any serotonergic medication.

Source

Mischoulon D, Fava M. J Clin Psychiatry 2002

⚠️ MODERATE INTERACTION: Monitor closely if this combination is used.

Disclaimer

This interaction record is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider before starting or stopping any supplement or medication.