Safety Profile: protein powder

Source: OpenFDA CAERS Database
Report Count: 50 adverse event reports
Date Range: 2007 - 2025

IMPORTANT DISCLAIMER: These are voluntary adverse event reports and do not establish causation. The FDA cautions that "generally only a small fraction of adverse events associated with any product is reported." Multiple products and reactions may be listed in a single report with no way to conclude which product caused which reaction.

Most Commonly Reported Reactions

Reaction	Report Count
DIARRHOEA	5
NAUSEA	5
VOMITING	5
DYSPNOEA	4
Dizziness	4
Nausea	4
Chest pain	3
Gastrointestinal disorder	3
PAIN	3
Abdominal pain upper	3

Reported Outcomes

Outcome	Count
Other Serious or Important Medical Event	33
Hospitalization	15
Visited a Health Care Provider	12
Other Serious Outcome	10
Visited Emergency Room	10

Notable Signals

The following adverse reactions have been reported 5 or more times:

DIARRHOEA (5 reports)
NAUSEA (5 reports)
VOMITING (5 reports)

Understanding This Data

The Center for Food Safety and Applied Nutrition Adverse Event Reporting System (CAERS) is a database that contains information on adverse event and product complaint reports submitted to FDA for foods, dietary supplements, and cosmetics. Reports are submitted by:

Healthcare professionals (physicians, pharmacists, nurses)
Consumers (patients, family members)
Manufacturers (when they receive serious adverse event reports)

Key Limitations:

Voluntary reporting - Not all adverse events are reported
No causation established - Reports describe associations, not causation
Multiple products - A single report may list multiple products
No dose information - Reports may not specify dosage or duration
Reporting bias - Serious events are more likely to be reported

FDA Guidance

For more information on how to interpret CAERS data, visit: - CFSAN Adverse Event Reporting System - FDA's CAERS Database Information