Pre- and Post-surgical Prevalence of Thiamine Deficiency in Patients Undergoing Bariatric Surgery: a Systematic Review and Meta-analysis

source extracted confidence: high 2026-04-09
#female #humans #pregnancy #bariatric-surgery #obesity

Pre- and Post-surgical Prevalence of Thiamine Deficiency in Patients Undergoing Bariatric Surgery: a Systematic Review and Meta-analysis

Karimi et al., 2024 | Obes Surg | Meta Analysis

Citation

Karimi Behnagh Arman, Eghbali Maryam, ... Mottaghi Azadeh. Pre- and Post-surgical Prevalence of Thiamine Deficiency in Patients Undergoing Bariatric Surgery: a Systematic Review and Meta-analysis. Obes Surg. 2024-Feb;34(2):653-665. doi:10.1007/s11695-023-06896-6

Abstract

Thiamine deficiency is a life-threatening nutritional abnormality observed in the patients with obesity and following bariatric surgery. The aim of the present study is to determine the prevalence of thiamine deficiency prior to and after bariatric procedures. PubMed, Web of Science, Google scholar, CENTRAL, ProQuest, and Scopus were searched to retrieve relevant studies containing data on thiamine deficiency in patients with obesity who underwent bariatric surgery. A proportional meta-analysis approach was used to pool the prevalence of thiamine deficiency prior and after surgery. Our comprehensive literature search retrieved 41 studies with relevant data. The pooled prevalence of thiamine deficiency was 7% (95% CI: 4-12%) at baseline. We observed that 19% (95% CI: 0-68%), 9% (95% CI: 3-17%), and 6% (95% CI: 3-9%) of patients had developed thiamine deficiency at 3 months, 6 months, and 1 year after surgery, respectively. We also report that the prevalence of thiamine deficiency in pregnant women who had history of bariatric surgery. The rate was highest in the first trimester (12%) compared to that in the second (8%) and third (10%) trimesters. The baseline prevalence is 7% for thiamine deficiency in bariatric surgery candidates. The prevalence rate of thiamin deficiency increased to 19% and 9% 3 and 6 months after surgery; however, the rate decreased to 6% 1 year after surgery. Due to the higher prevalence of thiamine deficiency in the early post-operative phase, close monitoring during this period is recommended. A similar strategy should be implemented for pregnant women with history of bariatric surgery in their first trimester.

Key Findings

A similar strategy should be implemented for pregnant women with history of bariatric surgery in their first trimester.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population pregnant women
Sample Size 41
Age Range See abstract
Condition deficiency

MeSH Terms

  • Female
  • Humans
  • Pregnancy
  • Bariatric Surgery
  • Obesity
  • Prevalence
  • Thiamine
  • Thiamine Deficiency

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Meta-Analysis, Systematic Review, Journal Article
  • Vertical: thiamine-energy

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09