Magnesium Glycinate
Product Forms
Dose Distribution
Top Brands
Claims on Labels
Common Co-Ingredients
Top-Rated Magnesium Glycinate Products
Chelated Magnesium 250 mg
VitaCeutical Labs
Magnesium Glycinate Forte
Douglas Laboratories
Amino Acid Chelated Magnesium
Newflower Farmers Markets
Amino Acid Chelated Magnesium
Newflower Farmers Markets
Magnesium Glycinate Chelate
Designs for Health
Claims vs. Evidence
75%
Evidence-Backed
25%
Unsupported
88%
Structure/Function
| Claim Type | % of Products | Evidence Required | Status |
|---|---|---|---|
| All Other | 100% | Tier D (Unclassified) | ✅ Supported |
| Structure/Function | 88% | Tier C (DSHEA Structure/Function (no pre-approval)) | ⚠️ Unsupported |
| Nutrient | 59% | Tier D (Unknown) | ✅ Supported |
| No Claim | 0% | Tier D (No claim on label) | ✅ Supported |
Research by Topic
Magnesium Sleep
1 studies
Research Evidence (1)
Clinical Trial: 1
B
Magnesium Bisglycinate Supplementation in Healthy Adults Reporting Poor Sleep: A Randomized, Placebo-Controlled Trial
PURPOSE: To assess the effects of magnesium bisglycinate supplementation on insomnia symptoms in healthy adults reporting poor sleep quality. PATIENTS AND METHODS: This randomized, double-blind, placebo-controlled trial enrolled 155 adults aged 18-65...
Details
Magnesium Glycinate
Overview
Magnesium glycinate (also called magnesium bisglycinate) is a chelated form of magnesium where magnesium is bound to two glycine molecules.
Properties
| Property | Value |
|---|---|
| Chemical Formula | Mg(C₂H₄NO₂)₂ |
| Bioavailability | High |
| Elemental Mg Content | ~14% |
| Absorption | Good, minimal laxative effect |
Advantages
- High bioavailability: Chelated form enhances absorption
- Gentle on GI: Minimal laxative effect compared to other forms
- Glycine synergy: Glycine itself may support sleep and relaxation
- Good tolerability: Well-tolerated at therapeutic doses
Evidence for Sleep
Clinical trials using magnesium glycinate/bisglycinate for sleep: - Schuster et al. 2025 (PMID: 40918053): 250mg elemental Mg, 4 weeks, improved ISI scores - Generally shows positive results in sleep-deficient populations
Comparison to Other Forms
| Form | Bioavailability | GI Tolerance | Best For |
|---|---|---|---|
| Glycinate | High | Excellent | Sleep, anxiety, daily use |
| Citrate | High | Good | Constipation, general supplementation |
| Oxide | Low | Fair | Not recommended for CNS effects |
| Threonate | High | Good | Cognitive effects |
Related Entities
- magnesium — Parent mineral
- magnesium-citrate — Alternative form
- magnesium-oxide — Lower bioavailability form
- magnesium-threonate — Brain-focused form
Safety Notes
- Generally well-tolerated
- Less likely to cause diarrhea than citrate or oxide forms
- Standard dosing: 200-400mg elemental magnesium
Entity page for magnesium glycinate compound