⚠️ Mechanism
Curcumin may inhibit platelet aggregation and affect clotting, potentially additive with anticoagulants.
📋 Effect
Possible increased bleeding risk at high supplemental doses
💊 Management
Monitor INR with warfarin. Avoid high-dose turmeric supplements before surgery.
Plain Language Summary
This combination may increase your risk of bleeding. High doses of turmeric can affect how your blood clots, which may add to the effect of your medication.
Source
Shah BH et al. Biochem J 1999; Srivastava KC. Prostaglandins Leukot Essent Fatty Acids 1989
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.