⚠️ Mechanism
Interaction identified from DDInter 2.0 database. Specific drugs: Deferiprone
📋 Effect
See mechanism description
💊 Management
Consult healthcare provider before combining.
Plain Language Summary
This combination is considered moderately risky. Taking milk thistle with certain iron-removing drugs, such as deferiprone, may cause an interaction that affects how the medication works in your body.
Source
DDInter 2.0 (ddinter.scbdd.com)
Supporting Research
Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Pharmacotherapy for trichotillomania
Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease: A meta-analysis (PRISMA) of randomized control trials
Prevention and management of idiosyncratic drug-induced liver injury: Systematic review and meta-analysis of randomised clinical trials
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.