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Dong Quai × Warfarin

MODERATE INTERACTION — Probable Evidence

⚠️ Mechanism

Dong quai contains coumarin derivatives that may potentiate warfarin's anticoagulant effect.

📋 Effect

Increased INR; increased bleeding risk

💊 Management

Avoid dong quai with warfarin. Monitor INR closely if used.

Plain Language Summary

This combination can be dangerous because Dong Quai may increase the blood-thinning effects of warfarin. This increase in effect can lead to a higher risk of bleeding.

Source

Heck AM et al. Am J Health Syst Pharm 2000; Page RL, Lawrence JD. Pharmacotherapy 1999

Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.