Effects of chamomile and -theanine beverage on menstrual pain, menstrual symptoms, mood, and sleep quality in young women experiencing primary dysmenorrhea: A randomized, double-blind, placebo-controlled study
Effects of chamomile and -theanine beverage on menstrual pain, menstrual symptoms, mood, and sleep quality in young women experiencing primary dysmenorrhea: A randomized, double-blind, placebo-controlled study
Soh et al., 2025 | J Food Drug Anal | Rct
Citation
Soh Ziqing, Tan Soo Cing, ... Tan Chin Xuan. Effects of chamomile and -theanine beverage on menstrual pain, menstrual symptoms, mood, and sleep quality in young women experiencing primary dysmenorrhea: A randomized, double-blind, placebo-controlled study. J Food Drug Anal. 2025-Dec-15;33(4):381-390. doi:10.38212/2224-6614.3565
Abstract
Primary dysmenorrhea is one of the most common complaints among young women. This study aimed to evaluate the effects of chamomile and 1-theanine beverage intake on menstrual symptoms, pain intensity, mood, and sleep quality in young adult females with primary dysmenorrhea, using a two-phase continuous study design. In the first phase, a cross-sectional study was conducted to assess the prevalence of primary dysmenorrhea. In the second phase, participants were randomly assigned to either the intervention group (n = 15), which consumed chamomile and 1-theanine beverage (CTT), or the control group (n = 15), which consumed chamomile-flavored beverage (non-CTT). Beverages were consumed daily for five consecutive days, starting two days before the expected onset of menstruation and continuing through the first three days of menstruation. Compared to baseline values, consumption of CTT significantly reduced ( p < 0.001) visual analog scale and numerical rating scale values by 57.17% and 55.46%, respectively. Additionally, CTT intake led to significant reductions ( p < 0.05) in the severity of lower abdominal pain, loss of appetite, backpain, complexation, stomachache, body pain, depression, and irritability by 52.86%, 47.24%, 56.29%, 31.03%, 43.14%, 42.52%, 49.46%, 45.11%, respectively. CTT consumption also significantly decreased ( p < 0.05) daytime dysfunction by 31.97% compared to baseline. Meanwhile, non-CTT consumption significantly reduced ( p < 0.05) the severity of complexation, neuroticism, and confusion in the control group. The CTT beverage could be a potential alternative for managing primary dysmenorrhea. Further studies with longer durations are warranted to assess its potential long-term physiological effects.
Key Findings
Further studies with longer durations are warranted to assess its potential long-term physiological effects.
Outcomes Measured
- sleep quality
- depression
Population
| Field | Value |
|---|---|
| Population | young women |
| Sample Size | 15 |
| Age Range | See abstract |
| Condition | sleep |
MeSH Terms
- Adolescent
- Adult
- Female
- Humans
- Young Adult
- Affect
- Beverages
- Chamomile
- Cross-Sectional Studies
- Double-Blind Method
- Dysmenorrhea
- Glutamates
- Menstruation
- Plant Extracts
- Sleep Quality
Evidence Classification
- Level: Rct
- Publication Types: Journal Article, Randomized Controlled Trial
- Vertical: l-theanine-sleep
Provenance
- PMID: 41525193
- DOI: 10.38212/2224-6614.3565
- PMCID: PMC12795334
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09