Effects of laser treatment on bond strength of epoxy resin and calcium silicate-based sealers: a systematic review and meta-analysis of in vitro studies

source extracted confidence: high 2026-04-09
#epoxy-resins #silicates #root-canal-filling-materials #calcium-compounds #humans

Effects of laser treatment on bond strength of epoxy resin and calcium silicate-based sealers: a systematic review and meta-analysis of in vitro studies

da et al., 2024 | Clin Oral Investig | Meta Analysis

Citation

da Costa Ribeiro Carlos Eduardo Victor, Lena Isabella Marian, ... Morgental Renata Dornelles. Effects of laser treatment on bond strength of epoxy resin and calcium silicate-based sealers: a systematic review and meta-analysis of in vitro studies. Clin Oral Investig. 2024-Nov-16;28(12):644. doi:10.1007/s00784-024-06038-x

Abstract

OBJECTIVE: This study aimed to systematically review the effect of laser treatment on the bond strength of epoxy resin-based and calcium silicate-based endodontic sealers to root dentine. METHODS: The search encompassed four databases: PubMed/MEDLINE, EMBASE, Scopus, and ISI Web of Science. Inclusion criteria were limited to in vitro studies conducted on extracted human teeth evaluating bond strength in megapascals (MPa) of either epoxy resin-based or calcium silicate-based sealers, using the push-out test. Two independent reviewers appraised the methodological quality of the selected studies to assess the risk of bias. Meta-analysis was performed for different laser types, endodontic sealers, and control groups. Standard Mean Difference and 95% Confidence Interval values were calculated. RESULTS: 17 studies met the inclusion criteria for qualitative synthesis, and 15 for quantitative analysis. Meta-analyses revealed that certain lasers (Er,Cr:YSGG, Er:YAG) significantly increased bond strength for epoxy resin-based sealers when compared to negative controls (inert solutions), but did not show a significant advantage over EDTA agent. For calcium silicate-based sealers, laser treatment did not show significant enhancement in bond strength compared to either inert solutions or EDTA. The subgroup analysis suggested that erbium lasers, especially in the PIPS mode, potentially increase the bond strength of epoxy resin-based sealers. CONCLUSION: Laser treatment enhances the bond strength of epoxy resin-based sealers compared to inert solutions, but not more than EDTA. For calcium silicate-based sealers, laser treatment does not significantly improve bond strength over inert solutions or EDTA. CLINICAL RELEVANCE: Laser treatment increases the bond strength of epoxy resin-based sealers.

Key Findings

17 studies met the inclusion criteria for qualitative synthesis, and 15 for quantitative analysis. Meta-analyses revealed that certain lasers (Er,Cr:YSGG, Er:YAG) significantly increased bond strength for epoxy resin-based sealers when compared to negative controls (inert solutions), but did not show a significant advantage over EDTA agent. For calcium silicate-based sealers, laser treatment did not show significant enhancement in bond strength compared to either inert solutions or EDTA. The sub

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 17
Age Range See abstract
Condition See abstract

MeSH Terms

  • Epoxy Resins
  • Silicates
  • Root Canal Filling Materials
  • Calcium Compounds
  • Humans
  • Dental Bonding
  • In Vitro Techniques
  • Dental Stress Analysis

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Systematic Review, Meta-Analysis
  • Vertical: calcium

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09