Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence

source extracted confidence: high 2026-04-09
#aged #humans #aging #anti-inflammatory-agents #antioxidants

Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence

Nunes et al., 2024 | Nutrients | Systematic Review

Citation

Nunes Yandra Cervelim, Mendes Nathalia M, ... Marin Maria José Sanches. Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence. Nutrients. 2024-Aug-15;16(16). doi:10.3390/nu16162721

Abstract

Aging-related disorders pose significant challenges due to their complex interplay of physiological and metabolic factors, including inflammation, oxidative stress, and mitochondrial dysfunction. Curcumin, a natural compound with potent antioxidant and anti-inflammatory properties, has emerged as a promising candidate for mitigating these age-related processes. However, gaps in understanding the precise mechanisms of curcumin's effects and the optimal dosages for different conditions necessitate further investigation. This systematic review synthesizes current evidence on curcumin's potential in addressing age-related disorders, emphasizing its impact on cognitive function, neurodegeneration, and muscle health in older adults. By evaluating the safety, efficacy, and mechanisms of action of curcumin supplementation, this review aims to provide insights into its therapeutic potential for promoting healthy aging. A systematic search across three databases using specific keywords yielded 2256 documents, leading to the selection of 15 clinical trials for synthesis. Here, we highlight the promising potential of curcumin as a multifaceted therapeutic agent in combating age-related disorders. The findings of this review suggest that curcumin could offer a natural and effective approach to enhancing the quality of life of aging individuals. Further research and well-designed clinical trials are essential to validate these findings and optimize the use of curcumin in personalized medicine approaches for age-related conditions.

Key Findings

Further research and well-designed clinical trials are essential to validate these findings and optimize the use of curcumin in personalized medicine approaches for age-related conditions.

Outcomes Measured

  • inflammatory markers

Population

Field Value
Population older adults
Sample Size See abstract
Age Range See abstract
Condition stress

MeSH Terms

  • Aged
  • Humans
  • Aging
  • Anti-Inflammatory Agents
  • Antioxidants
  • Cognition
  • Curcumin
  • Dietary Supplements
  • Healthy Aging
  • Oxidative Stress
  • Quality of Life

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: curcumin

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09