Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies

source extracted confidence: high 2026-04-09
#humans #tea #prospective-studies #risk #coronary-disease

Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies

Wang et al., 2023 | Nutr Metab Cardiovasc Dis | Meta Analysis

Citation

Wang Ze-Mu, Zhao Di, ... Wang Lian-Sheng. Green tea consumption and the risk of coronary heart disease: A systematic review and meta-analysis of cohort studies. Nutr Metab Cardiovasc Dis. 2023-Apr;33(4):715-723. doi:10.1016/j.numecd.2023.01.017

Abstract

BACKGROUND AND AIMS: Conflicting evidence exists regarding the association between green tea consumption and the risk of coronary heart disease (CHD). We performed a meta-analysis to determine whether an association exists between them in cohort studies. METHODS AND RESULTS: We searched the PubMed and EMBASE databases for studies conducted until September 2022. Prospective cohort studies that provided relative risk (RR) estimates with 95% confidence intervals (CIs) for the association were included. Study-specific risk estimates were combined using a random-effects model. A total of seven studies, with 9211 CHD cases among 772,922 participants, were included. We observed a nonlinear association between green tea consumption and the risk of CHD (P for nonlinearity = 0.0009). Compared with nonconsumers, the RRs (95% CI) of CHD across levels of green tea consumption were 0.89 (0.83, 0.96) for 1 cup/day (1 cup = 300 ml), 0.84 (0.77, 0.93) for 2 cups/day, 0.85 (0.77, 0.92) for 3 cups/day, 0.88 (0.81, 0.96) for 4 cups/day, and 0.92 (0.82, 1.04) for 5 cups/day. CONCLUSIONS: This updated meta-analysis of studies from East Asia suggests that green tea consumption may be associated with a reduced risk of CHD, especially among those with low-to-moderate consumption. Additional cohorts are still needed before we could draw a definitive conclusion. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42022357687.

Key Findings

We searched the PubMed and EMBASE databases for studies conducted until September 2022. Prospective cohort studies that provided relative risk (RR) estimates with 95% confidence intervals (CIs) for the association were included. Study-specific risk estimates were combined using a random-effects model. A total of seven studies, with 9211 CHD cases among 772,922 participants, were included. We observed a nonlinear association between green tea consumption and the risk of CHD (P for nonlinearity = 

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 772922
Age Range See abstract
Condition See abstract

MeSH Terms

  • Humans
  • Tea
  • Prospective Studies
  • Risk
  • Coronary Disease
  • Plant Extracts
  • Risk Factors

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Meta-Analysis, Systematic Review, Journal Article, Research Support, Non-U.S. Gov't
  • Vertical: green-tea

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09