Plant Adaptogens-History and Future Perspectives

Todorova et al., 2021 | Nutrients | Meta Analysis

Citation

Todorova Velislava, Ivanov Kalin, ... Ivanova Stanislava. Plant Adaptogens-History and Future Perspectives. Nutrients. 2021-Aug-20;13(8). doi:10.3390/nu13082861

Abstract

Adaptogens are synthetic compounds (bromantane, levamisole, aphobazole, bemethyl, etc.) or plant extracts that have the ability to enhance the body's stability against physical loads without increasing oxygen consumption. Extracts from Panax ginseng, Eleutherococcus senticosus, Rhaponticum carthamoides, Rhodiola rosea, and Schisandra chinensis are considered to be naturally occurring adaptogens and, in particular, plant adaptogens. The aim of this study is to evaluate the use of plant adaptogens in the past and now, as well as to outline the prospects of their future applications. The use of natural adaptogens by humans has a rich history-they are used in recovery from illness, physical weakness, memory impairment, and other conditions. About 50 years ago, plant adaptogens were first used in professional sports due to their high potential to increase the body's resistance to stress and to improve physical endurance. Although now many people take plant adaptogens, the clinical trials on human are limited. The data from the meta-analysis showed that plant adaptogens could provide a number of benefits in the treatment of chronic fatigue, cognitive impairment, and immune protection. In the future, there is great potential to register medicinal products that contain plant adaptogens for therapeutic purposes.

Key Findings

In the future, there is great potential to register medicinal products that contain plant adaptogens for therapeutic purposes.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition stress

MeSH Terms

  • Adaptation, Physiological
  • Adolescent
  • Adult
  • Animals
  • Female
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Male
  • Middle Aged
  • Phytotherapy
  • Plant Extracts
  • Stress, Physiological
  • Young Adult

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Historical Article, Journal Article, Meta-Analysis, Systematic Review
  • Vertical: ginseng

Provenance


Source extracted via PubMed E-utilities API on 2026-04-09