Bioavailability of magnesium food supplements: A systematic review

source extracted confidence: high 2026-04-09
#aged #biological-availability #dietary-supplements #humans #magnesium

Bioavailability of magnesium food supplements: A systematic review

Pardo et al., 2021 | Nutrition | Systematic Review

Citation

Pardo Marta R, Garicano Vilar Elena, ... Camina Martín María Alicia. Bioavailability of magnesium food supplements: A systematic review. Nutrition. 2021-Sep;89:111294. doi:10.1016/j.nut.2021.111294

Abstract

OBJECTIVES: The market for food supplements is booming thanks to their increased consumption. European regulations include different ways in which vitamins and minerals are administered, without making it clear to the consumer whether one formulation has advantages over the other. The aim of this review was to compare the bioavailability of different forms of magnesium and analyze the differences between them. METHODS: Based on a PICO (population, intervention, comparison, outcome) research question, a search strategy was established for magnesium bioavailability studies comparing different forms in the PubMed, Cochrane, Web of Science, and Scopus databases. We found 433 studies, out of which 14 were finally selected. RESULTS: Inorganic formulations appear to be less bioavailable than organic ones, and the percentage of absorption is dose dependent. CONCLUSIONS: All magnesium dietary supplements can maintain physiological levels in healthy people without prior deficit, although this cannot be assured in older people or those with illnesses or previous subphysiological levels.

Key Findings

Inorganic formulations appear to be less bioavailable than organic ones, and the percentage of absorption is dose dependent.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population healthy people
Sample Size 433
Age Range See abstract
Condition See abstract

MeSH Terms

  • Aged
  • Biological Availability
  • Dietary Supplements
  • Humans
  • Magnesium
  • Minerals
  • Vitamins

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: magnesium

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09