Mushroom Consumption and Cardiovascular Health: A Systematic Review
Mushroom Consumption and Cardiovascular Health: A Systematic Review
Krittanawong et al., 2021 | Am J Med | Systematic Review
Citation
Krittanawong Chayakrit, Isath Ameesh, ... Tang W H Wilson. Mushroom Consumption and Cardiovascular Health: A Systematic Review. Am J Med. 2021-May;134(5):637-642.e2. doi:10.1016/j.amjmed.2020.10.035
Abstract
INTRODUCTION: Edible mushrooms have a great nutritional value including high protein, essential amino acids, fiber, vitamins (B1, B2, B12, C, and D), minerals (calcium [Ca], potassium [K], magnesium [Mg], sodium [Na], phosphorus [P], copper [Cu], iron [Fe], manganese [Mn], and selenium [Se]), low fatty foods, and sodium. The objective of this systematic review was to determine the relationship between edible mushroom consumption and overall cardiovascular risk. METHODS: We systematically searched Ovid MEDLINE, Embase, Ovid Cochrane Database of Systematic Reviews, Scopus, and Web of Science from database inception from 1966 through August 2020 for observational studies that reported the association between edible mushroom consumption and cardiovascular risk. Two investigators independently reviewed data. Conflicts were resolved through consensus discussion. RESULTS: Of 1479 studies, we identified 7 prospective studies. Edible mushroom consumption may have favorable effects on lipid profiles by changing some metabolic markers such as low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, total cholesterol, and triglycerides. Moreover, edible mushroom consumption is probably associated with reduced mean blood pressure. The beneficial overall cardiovascular risk, stroke risk, and coronary artery disease of edible mushroom consumption are not consistent. CONCLUSIONS: Edible mushroom consumption has not been shown to conclusively affect cardiovascular risk factors to date. However, potential health benefits may exist, including a favorable alteration of lipid profiles and blood pressure reduction.
Key Findings
Of 1479 studies, we identified 7 prospective studies. Edible mushroom consumption may have favorable effects on lipid profiles by changing some metabolic markers such as low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, total cholesterol, and triglycerides. Moreover, edible mushroom consumption is probably associated with reduced mean blood pressure. The beneficial overall cardiovascular risk, stroke risk, and coronary artery disease of edible mushroom consum
Outcomes Measured
- blood pressure
Population
| Field | Value |
|---|---|
| Population | See abstract |
| Sample Size | 1479 |
| Age Range | See abstract |
| Condition | blood pressure |
MeSH Terms
- Agaricales
- Blood Pressure
- Cardiovascular Diseases
- Heart Disease Risk Factors
- Humans
- Lipids
Evidence Classification
- Level: Systematic Review
- Publication Types: Journal Article, Systematic Review
- Vertical: selenium
Provenance
- PMID: 33309597
- DOI: 10.1016/j.amjmed.2020.10.035
- PMCID: Not in PMC
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09