Nutraceuticals in Thyroidology: A Review of in Vitro, and in Vivo Animal Studies

Benvenga et al., 2020 | Nutrients | Systematic Review

Citation

Benvenga Salvatore, Ferrari Silvia Martina, ... Fallahi Poupak. Nutraceuticals in Thyroidology: A Review of in Vitro, and in Vivo Animal Studies. Nutrients. 2020-May-08;12(5). doi:10.3390/nu12051337

Abstract

Nutraceuticals are defined as a food, or parts of a food, that provide medical or health benefits, including the prevention of different pathological conditions, and thyroid diseases, or the treatment of them. Nutraceuticals have a place in complementary medicines, being positioned in an area among food, food supplements, and pharmaceuticals. The market of certain nutraceuticals such as thyroid supplements has been growing in the last years. In addition, iodine is a fundamental micronutrient for thyroid function, but also other dietary components can have a key role in clinical thyroidology. Here, we have summarized the in vitro, and in vivo animal studies present in literature, focusing on the commonest nutraceuticals generally encountered in the clinical practice (such as carnitine, flavonoids, melatonin, omega-3, resveratrol, selenium, vitamins, zinc, and inositol), highlighting conflicting results. These experimental studies are expected to improve clinicians' knowledge about the main supplements being used, in order to clarify the potential risks or side effects and support patients in their use.

Key Findings

These experimental studies are expected to improve clinicians' knowledge about the main supplements being used, in order to clarify the potential risks or side effects and support patients in their use.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Animals
  • Carnitine
  • Dietary Supplements
  • Fatty Acids, Omega-3
  • Flavonoids
  • Homeostasis
  • Humans
  • Inositol
  • Iodine
  • Melatonin
  • Resveratrol
  • Selenium
  • Thyroid Diseases
  • Thyroid Gland
  • Vitamins
  • Zinc

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: selenium

Provenance


Source extracted via PubMed E-utilities API on 2026-04-09