Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials

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#colorectal-neoplasms #digestive-system #female #zingiber-officinale #humans

Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials

Anh et al., 2020 | Nutrients | Systematic Review

Citation

Anh Nguyen Hoang, Kim Sun Jo, ... Kwon Sung Won. Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials. Nutrients. 2020-Jan-06;12(1). doi:10.3390/nu12010157

Abstract

Clinical applications of ginger with an expectation of clinical benefits are receiving significant attention. This systematic review aims to provide a comprehensive discussion in terms of the clinical effects of ginger in all reported areas. Following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guideline, randomized controlled trials on the effects of ginger were investigated. Accordingly, 109 eligible papers were fully extracted in terms of study design, population characteristics, evaluation systems, adverse effects, and main outcomes. The reporting quality of the included studies was assessed based on the Cochrane Collaboration's tool for assessing the risk of bias in randomized trials and integrated together with studies that investigated the same subjects. The included studies that examined the improvement of nausea and vomiting in pregnancy, inflammation, metabolic syndromes, digestive function, and colorectal cancer's markers were consistently supported, whereas other expected functions were relatively controversial. Nevertheless, only 43 clinical trials (39.4%) met the criterion of having a 'high quality of evidence.' In addition to the quality assessment result, small populations and unstandardized evaluation systems were the observed shortcomings in ginger clinical trials. Further studies with adequate designs are warranted to validate the reported clinical functions of ginger.

Key Findings

Further studies with adequate designs are warranted to validate the reported clinical functions of ginger.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition inflammation

MeSH Terms

  • Colorectal Neoplasms
  • Digestive System
  • Female
  • Zingiber officinale
  • Humans
  • Inflammation
  • Metabolic Syndrome
  • Nausea
  • Phytotherapy
  • Plant Extracts
  • Pregnancy
  • Pregnancy Complications
  • Randomized Controlled Trials as Topic
  • Vomiting

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: ginger

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09