Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review

source extracted confidence: high 2026-04-09
#appetite-depressants #appetite-regulation #feeding-behavior #female #humans

Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review

Stuby et al., 2019 | Nutrients | Systematic Review

Citation

Stuby Johann, Gravestock Isaac, ... Burgstaller Jakob M. Appetite-Suppressing and Satiety-Increasing Bioactive Phytochemicals: A Systematic Review. Nutrients. 2019-Sep-17;11(9). doi:10.3390/nu11092238

Abstract

The prevalence of obesity is increasing worldwide. Bioactive phytochemicals in food supplements are a trending approach to facilitate dieting and to improve patients' adherence to reducing food and caloric intake. The aim of this systematic review was to assess efficacy and safety of the most commonly used bioactive phytochemicals with appetite/hunger-suppressing and/or satiety/fullness-increasing properties. To be eligible, studies needed to have included at least 10 patients per group aged 18 years or older with no serious health problems except for overweight or obesity. Of those studies, 32 met the inclusion criteria, in which 27 different plants were tested alone or as a combination, regarding their efficacy in suppressing appetite/hunger and/or increasing satiety/fullness. The plant extracts most tested were derived from Camellia sinensis (green tea), Capsicum annuum, and Coffea species. None of the plant extracts tested in several trials showed a consistent positive treatment effect. Furthermore, only a few adverse events were reported, but none serious. The findings revealed mostly inconclusive evidence that the tested bioactive phytochemicals are effective in suppressing appetite/hunger and/or increasing satiety/fullness. More systematic and high quality clinical studies are necessary to determine the benefits and safety of phytochemical complementary remedies for dampening the feeling of hunger during dieting.

Key Findings

More systematic and high quality clinical studies are necessary to determine the benefits and safety of phytochemical complementary remedies for dampening the feeling of hunger during dieting.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 10
Age Range See abstract
Condition See abstract

MeSH Terms

  • Appetite Depressants
  • Appetite Regulation
  • Feeding Behavior
  • Female
  • Humans
  • Male
  • Obesity
  • Phytochemicals
  • Randomized Controlled Trials as Topic
  • Satiety Response
  • Treatment Outcome
  • Weight Loss

Evidence Classification

  • Level: Systematic Review
  • Publication Types: Journal Article, Systematic Review
  • Vertical: green-tea

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09