Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis

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#animals #antioxidants #dietary-supplements #female #food

Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis

Ullah et al., 2018 | Ecotoxicol Environ Saf | Meta Analysis

Citation

Ullah Habib, Liu Guijian, ... Mian Md Manik. Developmental selenium exposure and health risk in daily foodstuffs: A systematic review and meta-analysis. Ecotoxicol Environ Saf. 2018-Mar;149:291-306. doi:10.1016/j.ecoenv.2017.11.056

Abstract

Selenium (Se) is a trace mineral and an essential nutrient of vital importance to human health in trace amounts. It acts as an antioxidant in both humans and animals, immunomodulator and also involved in the control of specific endocrine pathways. The aim of this work is to provide a brief knowledge on selenium content in daily used various foodstuffs, nutritional requirement and its various health consequences. In general, fruits and vegetables contain low content of selenium, with some exceptions. Selenium level in meat, eggs, poultry and seafood is usually high. For most countries, cereals, legumes, and derivatives are the major donors to the dietary selenium intake. Low level of selenium has been related with higher mortality risk, dysfunction of an immune system, and mental failure. Selenium supplementation or higher selenium content has antiviral outcomes and is necessary for effective reproduction of male and female, also decreases the threat of chronic disease (autoimmune thyroid). Generally, some advantages of higher content of selenium have been shown in various potential studies regarding lung, colorectal, prostate and bladder cancers risk, nevertheless results depicted from different trials have been diverse, which perhaps indicates the evidence that supplementation will merely grant advantage if the intakes of a nutrient is deficient. In conclusion, the over-all people should be advised against the usage of Se supplements for prevention of cardiovascular, hepatopathies, or cancer diseases, as advantages of Se supplements are still ambiguous, and their haphazard usage could result in an increased Se toxicity risk. The associations among Se intake/status and health, or disease risk, are complicated and need exposition to notify medical practice, to improve dietary recommendations, and to develop adequate communal health guidelines.

Key Findings

The associations among Se intake/status and health, or disease risk, are complicated and need exposition to notify medical practice, to improve dietary recommendations, and to develop adequate communal health guidelines.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Animals
  • Antioxidants
  • Dietary Supplements
  • Female
  • Food
  • Humans
  • Male
  • Nutritional Requirements
  • Reproduction
  • Risk
  • Selenium
  • Trace Elements

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Systematic Review
  • Vertical: selenium

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09