Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis

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#angina-unstable #drugs-chinese-herbal #electrocardiography #heart #humans

Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis

Song et al., 2017 | Phytother Res | Meta Analysis

Citation

Song Haiying, Wang Peili, ... Wang Chenglong. Panax notoginseng Preparations for Unstable Angina Pectoris: A Systematic Review and Meta-Analysis. Phytother Res. 2017-Aug;31(8):1162-1172. doi:10.1002/ptr.5848

Abstract

This paper assessed the evidence of Panax notoginseng preparations in patients suffering from UAP using meta-analysis and systematic review methods. Methods were according to the Cochrane Handbook and analysed using Revman 5.3. A search of PubMed, Cochrane Library, Embase, MEDLINE, Chinese national knowledge infrastructure (CNKI), Vip information database, Wanfang data and Chinese Biomedical Literature Database (SinoMed) was conducted to identify randomized controlled trials (RCTs) of P. notoginseng preparations on UAP regardless of blinding, sex and language. The outcomes include all-cause mortality, cardiac mortality, cardiovascular events, UAP symptoms, improvement of electrocardiogram and adverse events. Eighteen RCTs including 1828 patients were identified. The level of reporting is generally poor. Among 18 studies, 16 studies were prescribed P. notoginseng injections, and two studies were oral P. notoginseng preparations. Reduction of cardiovascular events (RR:0.35;95% CI:0.13 to 0.94), alleviation of angina pectoris symptoms (RR:1.23;95% CI 1.18 to 1.29), improvement of ECG (RR:1.22;95% CI 1.15 to 1.28) and reduced frequency of angina pectoris (MD:-1.48; 95% CI -2.49 to -0.48) were observed. Cardiac mortality and duration of angina pectoris were not statistically significant. Panax notoginseng is beneficial to UAP patients; the results of these reviews may have important implications to clinical work. Copyright © 2017 John Wiley & Sons, Ltd.

Key Findings

Copyright © 2017 John Wiley & Sons, Ltd.

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size 1828
Age Range See abstract
Condition See abstract

MeSH Terms

  • Angina, Unstable
  • Drugs, Chinese Herbal
  • Electrocardiography
  • Heart
  • Humans
  • Panax notoginseng
  • Randomized Controlled Trials as Topic

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: Journal Article, Meta-Analysis, Systematic Review
  • Vertical: ginseng

Provenance

Source extracted via PubMed E-utilities API on 2026-04-09