Effect of Preexercise Creatine Ingestion on Muscle Performance in Healthy Aging Males

Baker et al., 2016 | J Strength Cond Res | Rct

Citation

Baker Taylor P, Candow Darren G, Farthing Jonathan P. Effect of Preexercise Creatine Ingestion on Muscle Performance in Healthy Aging Males. J Strength Cond Res. 2016-Jun;30(6):1763-6. doi:10.1519/JSC.0000000000001254

Abstract

Preexercise creatine supplementation may have a beneficial effect on aging muscle performance. Using a double-blind, repeated measures, crossover design, healthy males (N = 9, 54.8 ± 4.3 years; 92.9 ± 11.5 kg; 179.2 ± 11.1 cm) were randomized to consume creatine (20 g) and placebo (20 g corn starch maltodextrin), on 2 separate occasions (7 days apart), 3 hours before performing leg press and chest press repetitions to muscle fatigue (3 sets at 70% 1-repetition maximum; 1 minute rest between sets). There was a set main effect (p ≤ 0.05) for the leg press and chest press with the number of repetitions performed decreasing similarly for creatine and placebo. These results suggest that a bolus ingestion of creatine consumed 3 hours before resistance exercise has no effect on upper or lower-body muscle performance in healthy aging males.

Key Findings

These results suggest that a bolus ingestion of creatine consumed 3 hours before resistance exercise has no effect on upper or lower-body muscle performance in healthy aging males.

Outcomes Measured

Requires manual extraction

Population

Field	Value
Population	healthy aging
Sample Size	9
Age Range	See abstract
Condition	See abstract

MeSH Terms

Aging
Creatine
Cross-Over Studies
Dietary Supplements
Double-Blind Method
Exercise
Humans
Male
Middle Aged
Muscle Fatigue
Muscle, Skeletal

Evidence Classification

Level: Rct
Publication Types: Journal Article, Randomized Controlled Trial
Vertical: creatine-aging

Provenance

PMID: 26562708
DOI: 10.1519/JSC.0000000000001254
PMCID: Not in PMC
Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09