[Meta-analysis on the relationship between Chinese children's intelligence and excessive iodine]

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#adolescent #child #child-nutritional-physiological-phenomena #china #female

[Meta-analysis on the relationship between Chinese children's intelligence and excessive iodine]

Ren et al., 2014 | Wei Sheng Yan Jiu | Meta Analysis

Citation

Ren Sisi, Zhong Zhaohui. [Meta-analysis on the relationship between Chinese children's intelligence and excessive iodine]. Wei Sheng Yan Jiu. 2014-Jan;43(1):133-8

Abstract

OBJECTIVE: To evaluate the relationship between Chinese children's intelligence and excessive iodine. METHODS: A computerized literature search was carried out to collect articles published before 2013. The study type was controlled experimental design. And then the statistical analysis was conducted by using RevMan 5.0 software. RESULTS: A total of 20 controlled studies were included in Meta-analysis. The results showed that iodine content in 601 -900 microg/L (MD = -2.00, 95% CI -3.97, -0.03) and greater than 900 microg/L (MD = -2.77, 95% CI -4.02, -1.52) would reduce the intellectual level of children. Iodine content in 150-300 microg/L (MD = 0.33, 95% CI -0.76, 1.42) and 301-600 microg/L (MD = -1.09, 95% CI -4.80, 2.63) had not statistically significant. The results of dose-response analysis revealed that the possibility of lower intelligence would increase by 57% (OR = 1.57, 95% CI 1.36, 1.78) when there was an increase of 200 microg/L in iodine content. CONCLUSION: Iodine content that was greater than 600 microg/L would reduce the intellectual level of children.

Key Findings

A total of 20 controlled studies were included in Meta-analysis. The results showed that iodine content in 601 -900 microg/L (MD = -2.00, 95% CI -3.97, -0.03) and greater than 900 microg/L (MD = -2.77, 95% CI -4.02, -1.52) would reduce the intellectual level of children. Iodine content in 150-300 microg/L (MD = 0.33, 95% CI -0.76, 1.42) and 301-600 microg/L (MD = -1.09, 95% CI -4.80, 2.63) had not statistically significant. The results of dose-response analysis revealed that the possibility of l

Outcomes Measured

  • Requires manual extraction

Population

Field Value
Population See abstract
Sample Size See abstract
Age Range See abstract
Condition See abstract

MeSH Terms

  • Adolescent
  • Child
  • Child Nutritional Physiological Phenomena
  • China
  • Female
  • Humans
  • Intelligence
  • Iodine
  • Male
  • Randomized Controlled Trials as Topic

Evidence Classification

  • Level: Meta Analysis
  • Publication Types: English Abstract, Journal Article, Meta-Analysis
  • Vertical: iodine-cognitive

Provenance

  • PMID: 24564126
  • DOI: (not available)
  • PMCID: Not in PMC
  • Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09