Meta-analysis of the effects of dietary vitamin E supplementation on α-tocopherol concentration and lipid oxidation in pork
Meta-analysis of the effects of dietary vitamin E supplementation on α-tocopherol concentration and lipid oxidation in pork
Trefan et al., 2011 | Meat Sci | Meta Analysis
Citation
Trefan L, Bünger L, ... Doeschl-Wilson A. Meta-analysis of the effects of dietary vitamin E supplementation on α-tocopherol concentration and lipid oxidation in pork. Meat Sci. 2011-Apr;87(4):305-14. doi:10.1016/j.meatsci.2010.11.002
Abstract
Meta-analyses have been carried out to quantify the effect of dietary vitamin E on α-tocopherol accumulation and on lipid oxidation in porcine M. longissimus. Published results of 13 (vitamin E accumulation) and 10 (lipid oxidation) experiments respectively were used for the analyses. After a number of standardization procedures, a nonlinear relationship was found between the supplementary vitamin E and the accumulation of α-tocopherol in pork which approached a maximum value of 6.4 μg/g tissue. Pork lipid oxidation levels were described in terms of Thiobarbituric Acid Reacting Substances (TBARS) values. The statistical analysis revealed significant effect of vitamin E dose, muscle α-tocopherol concentration and supplementation time on TBARS, resulting in two prediction models for lipid oxidation. Meta-analysis has proven to be a valuable tool for combining results from previous studies to quantify the effects of dietary vitamin E. Further studies, carried out with standardized experimental protocols would be beneficial for model validation and to increase the predictive power of the derived models.
Key Findings
Further studies, carried out with standardized experimental protocols would be beneficial for model validation and to increase the predictive power of the derived models.
Outcomes Measured
- Requires manual extraction
Population
| Field | Value |
|---|---|
| Population | See abstract |
| Sample Size | See abstract |
| Age Range | See abstract |
| Condition | See abstract |
MeSH Terms
- Animal Feed
- Animal Nutritional Physiological Phenomena
- Animals
- Diet
- Dietary Supplements
- Lipid Peroxidation
- Meat
- Muscles
- Nonlinear Dynamics
- Swine
- Thiobarbituric Acid Reactive Substances
- alpha-Tocopherol
Evidence Classification
- Level: Meta Analysis
- Publication Types: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't
- Vertical: vitamin-e
Provenance
- PMID: 21146329
- DOI: 10.1016/j.meatsci.2010.11.002
- PMCID: Not in PMC
- Verified: 2026-04-09 via PubMed E-utilities API
Source extracted via PubMed E-utilities API on 2026-04-09