Seborrhoeic dermatitis

Manríquez et al., 2007 | BMJ Clin Evid | Systematic Review

Citation

Manríquez Juan Jorge, Uribe Pablo. Seborrhoeic dermatitis. BMJ Clin Evid. 2007-Jul-01;2007

Abstract

INTRODUCTION: Seborrhoeic dermatitis affects at least 1-3% of the population. Malassezia (Pityrosporum) ovale is thought to be the causative organism, and causes inflammation involving T cells and complement. Seborrhoeic dermatitis tends to relapse after treatment. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of topical treatments for seborrhoeic dermatitis of the scalp in adults? What are the effects of topical treatments for seborrhoeic dermatitis of the face and body in adults? We searched: Medline, Embase, The Cochrane Library and other important databases up to February 2006 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). RESULTS: We found nine systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: bifonazole, emollients, ketoconazole, lithium succinate, selenium sulphide, tar shampoo, terbinafine, and topical steroids (betamethasone valerate, clobetasol propionate, clobetasone butyrate, hydrocortisone, mometasone furate).

Key Findings

We found nine systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.

Outcomes Measured

Requires manual extraction

Population

Field	Value
Population	See abstract
Sample Size	See abstract
Age Range	See abstract
Condition	inflammation

MeSH Terms

Administration, Oral
Administration, Topical
Dermatitis, Seborrheic
Face
Humans
Ketoconazole
Lithium
Malassezia
Remission Induction
Scalp Dermatoses

Evidence Classification

Level: Systematic Review
Publication Types: Journal Article, Systematic Review
Vertical: selenium

Provenance

PMID: 19454093
DOI: (not available)
PMCID: PMC2943817
Verified: 2026-04-09 via PubMed E-utilities API

Source extracted via PubMed E-utilities API on 2026-04-09