Synergy of Exercise and Nutrition in Preventing and Treating Frailty

NCT ID: NCT06975540 Phase: NA Status: COMPLETED Enrollment: 47 Completion: 2022-07-29

Conditions

Frail Elderly

Interventions

Multidomain physical exercise

Summary

The goal of this clinical study is to learn if combining a nutritional supplement with a multicomponent exercise program can help prevent and treat frailty in community dwelling older adults. The main questions it aims to answer is: Does combining a nutritional supplement (MERITENE) with a multicomponent exercise program improve frailty and functionality in older adults?

Researchers will compare:

  • A group receiving both the nutritional supplement and the exercise program (intervention group)
  • A control group receiving neither (control group)

Participants:

  • take the nutritional supplement (MERITENE, 30g twice a day) for 180 days
  • attend (3days/week) supervised exercise sessions as part of the multicomponent program for 180 days (if assigned to the intervention group).
  • undergo regular clinical evaluations for frailty, nutritional status, cognitive function, emotional state, and quality of life.

Measurements will include: Changes in frailty status, particularly gait speed, measured using Share-fi criteria, nutritional assessment using the Mini Nutritional Assessment (MNA), physical and cognitive assessments, including Edmonton Frail Scale, MMSE, and Short Physical Performance Battery (SPPB) and a complete biochemical and clinical blood analysis.

Primary Outcome

Frailty according to the Survey of Health, Ageing and Retirement in Europe Frailty Index (SHARE-FI)

Source

ClinicalTrials.gov