Treatment of Women With PCOS of Phenotype D
Treatment of Women With PCOS of Phenotype D
NCT ID: NCT06639698 Phase: NA Status: COMPLETED Enrollment: 24 Completion: 2025-06-30
Conditions
PCOS (Polycystic Ovary Syndrome)
Interventions
Diosgenin
Summary
In this study, female patients diagnosed with PCOS of phenotype D will be enrolled. They generally display the following characteristics: menstrual cycle alterations; polycystic ovary morphology at ultrasound; normal blood levels of androgen, particularly testosterone; no signs of clinical hyperandrogenism.
Current treatments for this condition include insulin sensitizers (such as metformin) and hormonal contraceptives. However, this specific phenotype of PCOS do not feature metabolic or hormonal alterations, and the efficacy of these treatments has lately been questioned.
In the present clinical trial, patients will be given a dietary supplement containing Dioscorea extract (source of Diosgenin, a natural analog of progesterone), vitamin D and alpha-lactalbumin for six month. Restoration of regular menstrual cycle and physiological ultrasound appearance of the ovaries will be the primary goal of the intervention.
Primary Outcome
Restoration of regular menstrual cycle